The Science Behind the A.G.E. Pill

The A.G.E. Pill is about the closest thing to the fountain of youth that modern science has been able to produce so far. If you’re into anti-ageing and would like to have your metabolic markers return to where they were in your 20’s then what you’re about to read is for you.

Glycation and Ageing

The term A.G.E. is actually an acronym for “Anti Glycation Extreme”. So what is glyacation? Glycation is what occurs when blood glucose molecules bond with protein molecules in our bodies. The pathological impact of that unavoidable phenomenon is the formation of something called an advanced glycation end product. This happens to all of us … slowly … over a lifetime.

As children we had all the energy we needed, all day long. This energy is derived from metabolizing glucose sugar. As our bodies break down the glucose, the oxidation process releases the energy that powers the cells in our body. But unfortunately, a plaque-like residue is left over and forms a coating over the cells. This oxidized glucose plague is called “glycation”.

You can observe the effects of acute glycation in diabetes patients. People suffering from diabetes tend to age faster and along with that, they experience the early onset of degenerative diseases. This is due to poor sugar control.

At some level, the same thing is happening to every single one of us – just not to the same extreme, nor at the same rate. So in short, “glycation” is the result of lifelong glucose exposure – the metabolism of which is essential for life and energy, but it comes with this pathological “side effect”. The buildup of this plaque-like substance also interferes with inter-cellular (cell-to-cell) communication.

The Vital Role of Stem Cells

Now let’s talk briefly about stem cells. When we are young, our bodies grow quickly. We have an abundance of stem cells which are highly productive. These stem cells are the “master cells” in our bodies that are able to transform into any type of cell that we need. As we grow, the stem cells divide and multiply into the trillions of cells that comprise an adult body. Our stem cells also replace the cells in our bodies that wear out.

But when glycation occurs and plaque-like metabolized glucose residues attach themselves to the proteins in our stem cells, they create a kind of “barrier” or film over the stem cells, so that they slowly lose their efficiency and functionality. As a consequence, a cellular “sludge” forms inside the cells over time. The scientific name for this, is “lipofuscin“.

This lipofuscin ‘sludge’ buildup interferes with intra-cellular communication, both in our ‘regular’ cells, as well as our stem cells, so that they can no longer do the job they are supposed to do. As a consequence, the cell mitochondria are damaged – and because the mitochondria are like the “nuclear power plants” of our cells, we then find ourselves lacking energy.

Lack of energy and slowing down of regular bodily functions are the typical symptoms of ageing – lack of muscle strength, memory loss etc. Cell regeneration is inhibited, so that we no longer create as many cells as we lose in a day. This is what ageing is. Ageing is not a disease – it is a process.

To reverse ageing, we need a way to get back to 1:1 cell regeneration and efficient cell functionality. This is how it used to be when you were 20-25. Once you cross the 30 year old threshold, you begin to lose more cells than you create – and the cells that you do have don’t function internally as efficiently as they used to.

When lipofuscin caused by glycation is removed; when the cellular garbage is taken out of the stem cells, the mitochondria within the cells now have the ability to react by creating massive amounts of energy molecules and ATP-providing biological hydrogen which combines with the electrical energy of the body to make you feel like you have the energy of a teenager once again.

It doesn’t happen overnight. It’s a process – but most people are experiencing noticeable result within a month, especially if they drink plenty of water (which aids in the flushing out process).

Adenosine Triphosphate (ATP) and biological hydrogen are believed to be the keys in supporting the releases of vast stores of energy that are available to your body. Your new, elevated energy can help your cells to rebuild, rejuvenate and provide an environment to work at more optimum levels. Potentially providing support to alleviate the ravages to our bodies that occur over our lifetime.

Science Discovers the Significant Role of NAD+

Researchers at Harvard Medical School and the University of New South Wales discovered a natural compound that reverses the cumulative effects of aging ….. NAD+

In a paper published in Science Today, the team identifies a critical step in the molecular process that allows cells to repair damaged DNA.

Prof. Sinclair’s Uni NSW Team

Their experiments in mice suggest that a treatment is possible for DNA damage from ageing and radiation. It is so promising it has attracted the attention of NASA, which believes this new discovery can help its mission to Mars program.

While our cells have the innate capability to repair DNA damage – which happens every time we go out into the sun, for example – their ability to do this declines as we age.

The scientists identified that the metabolite NAD+, which is naturally present in every cell of our body, plays a key role as a regulator in protein-to-protein interactions that control DNA repair.

Treating mice with a NAD+ precursor, or “booster” called NMN was shown to improved their cells’ ability to repair DNA damage caused by radiation exposure or old age.

“The cells of the old mice were indistinguishable from the young mice, after just one week of treatment”, said lead author Professor David Sinclair of UNSW School of Medical Sciences and Harvard Medical School Boston.

“This is the closest we are to a safe and effective anti-ageing drug that’s perhaps only three to five years away from being on the market if the trials go well”, says Sinclair, who maintains a lab at UNSW in Sydney, Australia.

The A.G.E. Pill is the first to bring a complete NAD+ boosting nutraceutical product to market containing these exciting new anti-aging discoveries:- NAD+ precursor NR and proprietary supporting ingredients – which the body readily converts into NAD+.

The pharmaceutical version of an NAD+ booster is at least 3-5 years away and will likely be significantly more expensive after Human Trials, FDA approvals, and the legal patent process. Many of the scientists involved in the Harvard and UNSW research are already taking NAD+ boosting nutritional supplements just like those contained in Sisel’s A.G.E. Pill.

How the A.G.E Pill Reverses Ageing

According to The A.G.E. Pill scientist and formulator, Tom Mower, it provides four classes of advanced super-nutrients, which provide intense support for:

  1. Removing glycation plaque buildup that inhibit inter-cellular proteins.
  2. Supporting the stem cells’ internal system in breaking down the toxins and the cellular garbage that has built up and stimulating the creation of new stem cells.
  3. Cleaning up and reactivating ‘senile’ stem cells, allowing them to produce ATP-providing biological hydrogen, for energy. Theoretically, this could increase the electrical energy within our stem cells by 3-4 times, to a point where you might feel like you were 20 again.
  4. Improves DNA repair processes via stimulating the production of NAD+

This can lead to spectacular results in: weight loss, vision, hearing, blood pressure, organ repair, arthritis, diabetes, and many other issues. Within about 10 days to 2 weeks a person’s stem cells can be overhauled and repaired at the DNA molecular level.

Directions for use of the A.G.E. Pill

sisel age pillTake 6 capsules daily on an empty stomach – 3 capsules in the morning and 3 capsules in the evening, or 2 capsules, 3 times daily. For faster results, it is recommended to “double-dose” for the first month, then back off to the regular “6 capsules per day” maintenance dose.

Some have experienced what is called a “niacin rush” when double-dosing. It’s like that flushed feeling you get when you’re embarrassed and you can feel your ears burning. It’s completely harmless though. Drink plenty of water if this happens to you. In fact, for best results, drink plenty of water anyway.

Want to really push back against the effects of time? The A.G.E. Pill 2 pack gives you more of this powerful product for less. Use it to extend your regimen or to share your secret with family or friends. After all, feeling great is best when shared with others!

Warning: Do not take if pregnant, nursing, or under 18 years old. If you are taking prescription medication, or have a pre-existing medical condition, consult your healthcare provider before taking this product. Keep out of the reach of children. Do not use if tamper evident ring or seal is broken. This product may cause temporary reddening of the skin or flushing.


Want More? Learn About the Ingredients in the A.G.E. Pill Here


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If you prefer to watch a video which explains the process, here’s one that may interest you:













Add a Comment
  1. why is attempting to order the age pill such a convoluted process?

    1. Good question Bill. The ordering website is being totally redone and unfortunately, there have been some technical issues to overcome along the way. However, I’m told that they’re working tirelessly to refine everything and most issues have now been sorted out. Cheers.

  2. I still can not sign in

  3. The “Contact Us” link does not work. Does anyone know where I can purchase the 2 pack of the age pill which is supposed to be a better deal?
    There is a link for the 2 pack on the page where there are the screenshots of Facebook testimonials, but it just takes you to the website. And if I try to order 2, it just doubles the regular price.
    Thanks in advance for your assistance!

    1. You have to enrol as a “preferred customer” first. Then when you login, you’ll be able to find the 2 Pack deal.

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